Maternal microbiota: changes and consequences during pregnancy. a narrative review

Authors

  • Melany Tello-Silva Escuela Profesional de Enfermería, Facultad de Ciencias de la Salud, Universidad Peruana Unión, San Martín, Perú Author
  • Mardel Morales-García Universidad Peruana Unión, Lima, Perú Author
  • Liset Z. Sairitupa-Sanchez Universidad Peruana Unión, Lima, Perú Author
  • Víctor Álvarez-Manrique Escuela Profesional de Enfermería, Facultad de Ciencias de la Salud, Universidad Peruana Unión, San Martín, Perú Author
  • Víctor Álvarez-Manrique Escuela Profesional de Enfermería, Facultad de Ciencias de la Salud, Universidad Peruana Unión, San Martín, Perú Author
  • Noemí Perales Escuela Profesional de Enfermería, Facultad de Ciencias de la Salud, Universidad Peruana Unión, San Martín, Perú Author
  • Flor María-Vega Escuela Profesional de Enfermería, Facultad de Ciencias de la Salud, Universidad Peruana Unión, San Martín, Perú Author
  • Maritza Tuesta Pérez Escuela Profesional de Enfermería, Facultad de Ciencias de la Salud, Universidad Peruana Unión, San Martín, Perú Author
  • Noemí Tuanama Shupingahua Escuela Profesional de Enfermería, Facultad de Ciencias de la Salud, Universidad Peruana Unión, San Martín, Perú Author
  • Wilter C. Morales-García Dirección General de Investigación, Universidad Peruana Unión, Lima, Perú Author

DOI:

https://doi.org/10.62486/agsalud2025187

Keywords:

Microbiota, pregnant women, associated changes, natural changes

Abstract

Objective:This study aims to review the changes in microbiota during pregnancy, characterized by natural and associative aspects. Design: A literature review based on a narrative synthesis. Data Sources: The study was conducted using databases such as PubMed, Science Direct, Web of Science (WOS), Scielo, and Google Scholar. Study Selection: Documents were selected and analyzed through an exhaustive literature review, applying specific inclusion and exclusion criteria. Results: For the results analysis, 15 articles were selected, including 3 observational studies, 4 clinical trials, 7 statistical analyses, 2 systematic reviews, and 1 narrative review. The research population consisted of both healthy pregnant women and those with pre-existing conditions. Some studies were conducted in Europe, the United States, Australia, China, and South America. Conclusion: Changes in microbiota during pregnancy influence body mass index (BMI) and are associated with hypertensive disorders, gestational diabetes, the use of prebiotic supplements, and periodontitis. Moreover, microbiota is naturally linked to vaginal function changes, contributes to the infant’s immune system development, and provides beneficial bacteria through breast milk.

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Published

2025-02-18

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Review

How to Cite

1.
Tello-Silva M, Morales-García M, Sairitupa-Sanchez LZ, Álvarez-Manrique V, Álvarez-Manrique V, Perales N, et al. Maternal microbiota: changes and consequences during pregnancy. a narrative review. AG Salud [Internet]. 2025 Feb. 18 [cited 2025 May 22];3:187. Available from: https://agsalud.ageditor.org/index.php/agsalud/article/view/187