Resnet for Blood Sample Detection: A Study on Improving Diagnostic Accuracy

Authors

  • Arepalli Gopi Research Scholar, Department of Computer Science & Engineering, Annamalai University, Chidambaram, Tamilnadu, India Author
  • Sudha L.R Associate Professor, Department of Computer Science & Engineering, Annamalai University, Chidambaram, Tamilnadu, India Author
  • Iwin Thanakumar Joseph S Associate Professor, Department of Computer Science & Engineering, Koneru Lakshmaiah Education Foundation, Vaddeswaram, India Author

DOI:

https://doi.org/10.62486/agsalud2025193

Keywords:

Deep learning, Blood cells, ResNet, WBC (white blood cells), RBC(red blood cells), Platelets

Abstract

Automated blood cell analysis plays a crucial role in medical diagnostics, enabling rapid and accurate assessment of a patient's health status. In this paper, we provide a unique technique for detecting and classifying WBCs,RBCs, and platelets inside blood smear pictures using ResNet (Residual Neural Network), a deep learning architecture. Because of its capacity to efficiently train very deep neural networks while minimizing the vanishing gradient problem, the ResNet architecture has exhibited excellent performance in a variety of image recognition applications. Leveraging the power of ResNet, we developed a multi-class classification model capable of distinguishing between WBCs, RBCs, and platelets within microscopic images of blood smears. Our methodology involved preprocessing the blood smear images to enhance contrast and remove noise, followed by image segmentation to isolate individual blood cells and platelets. The segmented images were then used to train and fine-tune a ResNet model, utilizing a large annotated dataset of labeled blood cell images. The trained model exhibited remarkable accuracy in identifying and classifying different blood cell types, even in the presence of overlapping cells or artifacts. We extensively tested our suggested technique, on a range of blood smear images to evaluate its performance. The findings demonstrated that ResNet effectively identifies and categorizes WBCs, (RBCs) and platelets. When compared to methods our approach showcased superior accuracy, robustness and generalization capabilities. After training the model with the Resnet algorithm we got 92% of Accuracy

References

[1] He, K., Zhang, X., Ren, S., & Sun, J. (2015). Deep Residual Learning for Image Recognition. In Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition (CVPR).

[2] Shi, H., Li, P., Cheng, X., & Zhu, H. (2019). Leukocyte Identification and Quantification from Peripheral Blood Smear Slide Using Deep Learning. IEEE Access, 7, 16339-16347.

[3] Smith, A.B., Jones, C.D. (2019). "Automated Blood Cell and Platelet Detection using Convolutional Neural Networks." Journal of Medical Imaging, 42(3), 278-285.

[4] Li, S., Zong, X., & Jin, Z. (2020). A Red Blood Cell Morphological Abnormality Recognition Model Based on Deep Learning. Journal of Medical Systems, 44(3), 58.

[5] Zhang, Q., Xia, X., & Zou, Q. (2020). DeepCount: In-depth Platelet Detection in Microscopy Images with Deep Learning. Analytical and Bioanalytical Chemistry, 412(17), 4147-4156.

[6] Gao, Y., Li, J. (2018). "Platelet Abnormality Detection using Deep Convolutional Neural Networks." IEEE Journal of Biomedical and Health Informatics, 23(6), 2334-2341.

[7] Wang, F., Kong, H., & Liu, S. (2020). Complete Blood Cell Detection Based on Improved ResNet. IEEE Access, 8, 29922-29931.

[8] Perez, L., & Wang, J. (2017). The Effectiveness of Data Augmentation in Image Classification using Deep Learning. arXiv preprint arXiv:1712.04621.

[9] Zheng, Q., Wu, S. (2021). "Multiclass Detection of Blood

Cells and Platelets using Deep Learning Techniques." Journal of Biomedical Science and Engineering, 14, 245-256.

[10] Guan, Z., Yang, X., & Zhu, H. (2021). Leukocyte Classification via Fine-tuned ResNet. In International Conference on Medical Imaging and Virtual Reality (pp. 120-128). Springer.

[11] HemaSri, A., Sreenidhi, M. D., Chaitanya, V. V. K., Vasanth, G., Mohan, V. M., & Satish, T. (2023, March). Detection of RBCs, WBCs, Platelets Count in Blood Sample by using Deep Learning. In 2023 International Conference on Sustainable Computing and Data Communication Systems (ICSCDS) (pp. 47-51). IEEE.

[12] Alam, M. M., & Islam, M. T. (2019). Machine learning approach of automatic identification and counting of blood cells. Healthcare technology letters, 6(4), 103-108.

[13] Novia, L. U., Alipo-on, J. R. T., Escobar, F. I. F., Tan, M. J. T., Karim, H. A., & AlDahoul, N. (2023). White Blood Cell Classification of Porcine Blood Smear Images. In IAPR Workshop on Artificial Neural Networks in Pattern Recognition (pp. 156-168). Springer, Cham.

[14] Alhazmi, L. (2022). Detection of WBC, RBC, and Platelets in Blood Samples Using Deep Learning. BioMed Research International, 2022.

[15] Bramantya, A. A., Fatichah, C., & Suciati, N. DETECTION AND CLASSIFICATION OF RED BLOOD CELLS ABNORMALITY USING FASTER R-CNN AND GRAPH CONVOLUTIONAL NETWORKS.

[16] Lee, S. J., Chen, P. Y., & Lin, J. W. (2022). Complete Blood Cell Detection and Counting Based on Deep Neural Networks. Applied Sciences, 12(16), 8140.

[17] Safuan, S. N. M., Tomari, M. R. M., & Zakaria, W. N. W. (2022). Cross Validation Analysis of Convolutional Neural Network Variants with Various White Blood Cells Datasets for the Classification Task. International Journal of Online & Biomedical Engineering, 18(2).

[18] Patil, A. M., Patil, M. D., & Birajdar, G. K. (2021). White blood cells image classification using deep learning with canonical correlation analysis. Irbm, 42(5), 378-389.

[19] Khouani, A., El Habib Daho, M., Mahmoudi, S. A., Chikh, M. A., & Benzineb, B. (2020). Automated recognition of white blood cells using deep learning. Biomedical Engineering Letters, 10(3), 359-367.

[20] Tiwari, P., Qian, J., Li, Q., Wang, B., Gupta, D., Khanna, A., ... & de Albuquerque, V. H. C. (2018). Detection of subtype blood cells using deep learning. Cognitive Systems Research, 52, 1036-1044.

[21] Tammina, S. (2019). Transfer learning using vgg-16 with deep convolutional neural network for classifying images. International Journal of Scientific and Research Publications (IJSRP), 9(10), 143-150.

[22] Habibzadeh, M., Jannesari, M., Rezaei, Z., Baharvand, H., & Totonchi, M. (2018, April). Automatic white blood cell classification using pre-trained deep learning models: Resnet and inception. In Tenth international conference on machine vision (ICMV 2017) (Vol. 10696, pp. 274-281). SPIE.

[23] Kaur, P., Sharma, V., & Garg, N. (2016, March). Platelet count using image processing. In 2016 3rd International conference on computing for sustainable global development (INDIACom) (pp. 2574-2577). IEEE.

[24] Meenakshi, A., Ruth, J. A., Kanagavalli, V. R., & Uma, R. (2022). Automatic classification of white blood cells using deep features based convolutional neural network. Multimedia Tools and Applications, 1-22.

[25] Rahaman, M., Ali, M., Hossen, M., Nayer, M., Ahmed, K., & Bui, F. M. (2022). DCBC_DeepL: Detection and Counting of Blood Cells Employing Deep Learning and YOLOv5 Model. In International Conference on Artificial Intelligence and Data Science (pp. 203-214). Springer, Cham.

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Published

2025-01-01

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Section

Original

How to Cite

1.
Gopi A, Sudha L, Iwin Thanakumar JS. Resnet for Blood Sample Detection: A Study on Improving Diagnostic Accuracy. AG Salud [Internet]. 2025 Jan. 1 [cited 2024 Dec. 2];3:193. Available from: https://agsalud.ageditor.org/index.php/agsalud/article/view/193